League of Legends Patch: 9.23
Analysed 175,151 Platinum+ Vayne games this week

Vayne Highest Win Rune Page for Platinum+

PRECISION

Become a legend
Improved attacks and sustained damage

INSPIRATION

+18% Attack Speed

Press the Attack

51.15% Win 87.34% Pick

Hitting an enemy champion 3 consecutive times makes them vunerable, dealing bonus damage...

Magical Footwear

51.24% Win 44.98% Pick

You get free boots at 10 min but you cannot buy boots before then. Each takedown you get makes your boots...

Triumph

51.00% Win 89.67% Pick

Takedowns restore 12% of your missing health and grant an additional 20 gold.

Future's Market

51.99% Win 1.65% Pick

You can enter debt to buy items.

Legend: Bloodline

51.14% Win 17.15% Pick

Takedowns on enemies grant permanent Lifesteal.

Cut Down

51.68% Win 4.51% Pick

Deal more damage to champions with more max health than you.