League of Legends Patch: 9.4
Analysed 229,412 Platinum+ Vayne games this week

Vayne Highest Win Rune Page for Platinum+

PRECISION

Become a legend
Improved attacks and sustained damage

INSPIRATION

+18% Attack Speed

Fleet Footwork

53.38% Win 41.42% Pick

Attacking and moving builds Energy stacks. At 100 stacks, your next attack heals you and grants...

Magical Footwear

55.23% Win 1.48% Pick

You get free boots at 10 min but you cannot buy boots before then. Each takedown you get makes your boots...

Overheal

53.57% Win 21.20% Pick

Excess healing on you becomes a shield.

Biscuit Delivery

54.81% Win 1.02% Pick

Gain a free Biscuit every 3 min, until 12 min. Consuming a Biscuit permanently increases your max mana.

Legend: Alacrity

53.30% Win 70.12% Pick

Takedowns on enemies grant permanent Attack Speed.

Cut Down

53.58% Win 2.54% Pick

Deal more damage to champions with more max health than you.