League of Legends Patch: 9.16
Analysed 200,029 Platinum+ Vayne games this week

Vayne Highest Win Rune Page for Platinum+

PRECISION

Become a legend
Improved attacks and sustained damage

DOMINATION

+9% Attack Speed
+6 Attack Damage or +10 Ability Power, Adaptive

Press the Attack

50.28% Win 85.78% Pick

Hitting an enemy champion 3 consecutive times makes them vunerable, dealing bonus damage...

Taste of Blood

50.59% Win 30.26% Pick

Heal when you damage an enemy champion.

Triumph

50.15% Win 89.73% Pick

Takedowns restore 12% of your missing health and grant an additional 20 gold.

Eyeball Collection

50.86% Win 2.02% Pick

Collect eyeballs for champion and ward takedowns. Gain permanent AD or AP, adaptive for each...

Legend: Alacrity

50.23% Win 82.85% Pick

Takedowns on enemies grant permanent Attack Speed.

Coup de Grace

50.18% Win 90.73% Pick

Deal more damage to low health enemy champions.