League of Legends Patch: 8.23
Analysed 28,800 Platinum+ Syndra games this week

Syndra Highest Win Rune Page for Platinum+

DOMINATION

Hunt and eliminate prey
Burst damage and target access

INSPIRATION

+12 Attack Damage or +20 Ability Power, Adaptive

Electrocute

48.58% Win 41.07% Pick

Hitting a champion with 3 separate attacks or abilities in 3s deals bonus adaptive damage.

Magical Footwear

50.83% Win 3.75% Pick

You get free boots at 10 min but you cannot buy boots before then. Each takedown you get makes your boots...

Taste of Blood

49.15% Win 44.76% Pick

Heal when you damage an enemy champion.

Cosmic Insight

49.34% Win 9.50% Pick

+5% CDR
+5% Max CDR
+5% Summoner Spell CDR...

Eyeball Collection

48.55% Win 65.91% Pick

Collect eyeballs for champion and ward takedowns. Gain permanent AD or AP, adaptive for each...

Ravenous Hunter

49.12% Win 49.18% Pick

Unique takedowns grant permanent healing from ability damage.