League of Legends Patch: 8.23
Analysed 72,185 Platinum+ Lissandra games this week

Lissandra Highest Win Rune Page for Platinum+

RESOLVE

Live forever
Durability and crowd control

INSPIRATION

+30-270 Health based on level

Aftershock

51.55% Win 71.54% Pick

After immobilizing an enemy champion gain defenses and later deal a burst of adaptive damage...

Future's Market

50.61% Win 1.48% Pick

You can enter debt to buy items.

Demolish

51.88% Win 43.34% Pick

Charge up a powerful attack against a tower while near it.

Time Warp Tonic

51.82% Win 3.70% Pick

Your potions, biscuits and elixirs last 20% longer, and you gain 5% Movement Speed while under...

Conditioning

52.66% Win 2.66% Pick

After 10 min gain +8 Armor and +8 Magic Resist and increase your Armor and Magic Resist by 5%.

Overgrowth

51.90% Win 56.72% Pick

Gain additional permanent max health when minions or monsters die near you.