League of Legends Patch: 9.8
Analysed 68,245 Platinum+ Karthus games this week

Karthus Highest Win Rune Page for Platinum+

SORCERY

Unleash Destruction
Empowered abilities and resource manipulation

PRECISION

+8 Attack Damage or +14 Ability Power, Adaptive
+5.5% Attack Speed

Summon Aery

52.78% Win 5.98% Pick

Your attacks and abilities send Aery to a target, damaging enemies or shielding allies.

Presence of Mind

51.45% Win 85.27% Pick

Takedowns restore 20% of your maximum mana and refund 10% of your ultimate's cooldown.

Manaflow Band

51.94% Win 6.88% Pick

Hitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250...

Last Stand

55.13% Win 5.69% Pick

Deal more damage to champions while you are low on health.

Absolute Focus

54.12% Win 3.31% Pick

While above 70% health, gain extra adaptive damage.

Scorch

54.04% Win 4.12% Pick

Your first ability hit every 20s burns champions.