League of Legends Patch: 10.1
Analysed 174,888 Platinum+ Cassiopeia games this week

Cassiopeia Middle Highest Win Rune Page for Platinum+

PRECISION

Become a legend
Improved attacks and sustained damage

DOMINATION

+9% Attack Speed
+6 Attack Damage or +10 Ability Power, Adaptive

Conqueror

51.38% Win 73.35% Pick

After 4 seconds in combat, your first attack against an enemy champion grants you AD and...

Taste of Blood

51.64% Win 81.92% Pick

Heal when you damage an enemy champion.

Presence of Mind

51.64% Win 62.96% Pick

Takedowns restore 20% of your maximum mana and refund 10% of your ultimate's cooldown.

Ravenous Hunter

51.69% Win 84.21% Pick

Unique takedowns grant permanent healing from ability damage.

Legend: Tenacity

51.69% Win 65.41% Pick

Takedowns on enemies grant permanent Tenacity.

Last Stand

52.85% Win 8.92% Pick

Deal more damage to champions while you are low on health.