League of Legends Patch: 9.4
Analysed 37,303 Platinum+ Cassiopeia games this week

Cassiopeia Highest Win Rune Page for Platinum+

SORCERY

Unleash Destruction
Empowered abilities and resource manipulation

RESOLVE

+6 Attack Damage or +10 Ability Power, Adaptive
+15-135 Health based on level

Arcane Comet

51.47% Win 53.96% Pick

Damaging a champion with an ability hurls a damaging comet at their location.

Bone Plating

53.94% Win 1.05% Pick

After taking damage from an enemy champion, the next 3 spells or attacks you receive from enemy...

Nullifying Orb

51.52% Win 4.06% Pick

Gain a magic damage shield when taken to low health by magic damage.

Bone Plating

53.94% Win 1.05% Pick

After taking damage from an enemy champion, the next 3 spells or attacks you receive from enemy...

Transcendence

51.28% Win 47.15% Pick

Gain 10% CDR when you reach level 10. Excess CDR becomes AP or AD, adaptive.

Scorch

51.02% Win 56.04% Pick

Your first ability hit every 20s burns champions.