League of Legends Patch: 10.1
Analysed 55,048 Diamond+ Cassiopeia games this week

Cassiopeia Highest Win Rune Page for Diamond+

SORCERY

Unleash Destruction
Empowered abilities and resource manipulation

INSPIRATION

+12 Attack Damage or +20 Ability Power, Adaptive

Phase Rush

51.57% Win 22.73% Pick

Hitting an enemy champion with 3 attacks or separate abilities grats a burst of MS.

Biscuit Delivery

48.58% Win 3.51% Pick

Gain a free Biscuit every 3 min, until 12 min. Consuming a Biscuit permanently increases your max mana.

Nullifying Orb

52.80% Win 1.30% Pick

Gain a magic damage shield when taken to low health by magic damage.

Cosmic Insight

53.83% Win 1.35% Pick

+5% CDR
+5% Max CDR
+5% Summoner Spell CDR...

Celerity

51.69% Win 3.22% Pick

Gain 2% extra MS. Gain extra AP or AD, adaptive based on your bonus MS.

Gathering Storm

51.41% Win 10.46% Pick

Gain increasing amounts of AD or AP, adaptive over the course of the game.